American researchers have reversed some early signs of Alzheimer’s in a study that has shown that biomarkers in the blood of patients can be improved with lifestyle changes.
The preliminary results of the Biorand study, presented at the Annual Meeting of the American Academy of Neurology this month, indicate that non -pharmacological interventions can have a significant impact on brain health through prevention, based on simple blood tests and non -pharmacological interventions.
“The area uses biomarkers to determine whether someone has dementia or not,” said study’s lead author Kellyann Niotis, a risk reduction neurologist for Alzheimer’s and Parkinson.
The researcher stressed that there are no groups observing how biomarkers change over time to know how to measure a person’s progress by improving brain health.
“We believe that these biomarkers can show how the disease progression is being biologically modified by the patient’s own actions,” he said.
Read more: “OAB of Medicine” advances in Congress and divides opinions between entities
Continues after advertising
What the study analyzed
The research followed 71 participants, 54 received personalized guidelines for neurological prevention. The other 17 formed the control group. Scientists evaluated more than 125 biomarkers in commercial and research tests, with special focus on some proteins.
Tracking these markers is essential when it comes to the disease, as they appear in the body even before clinical symptoms.
The reduction is considered indicative of improving brain health, possibly before cognitive decline is irreversibly installed.
Continues after advertising
Read more: intestine cancer tracking identifies lesions in 231 patients
Interventions
Scientists recommended specific changes such as blood pressure control, food changes, regular exercise, sleep quality improvement, stress reduction and nutritional supplementation.
These guidelines already have scientific support, which relates modifiable factors such as physical inactivity, poor diet, obesity, hypertension and sleep apnea, to the increased risk of dementia.
Continues after advertising
Other research has already shown that adopting a healthy lifestyle can significantly decrease this risk, even in people with genetic predisposition.
In the case of Bioorand, there is a validation of these effects through objective and quantifiable examinations. According to the survey, participants who followed at least 60% of these recommendations were included in the high adhesion group.
“These markers show how the brain is biologically responding to change. For the first time, we managed to measure this progress in real time,” said Niotis.
Continues after advertising
Diagnosis
Blood tests are seen as a more affordable and less invasive path to early Alzheimer’s diagnosis, with the ability to replace more aggressive methods such as lumbar punches or high -cost imaging exams.
In the long run, the idea is for these tests to function as a kind of “brain cholesterol”, helping to measure risk and guide preventive care since middle age.
Scientists intend to turn this panel of exams into an affordable tool at lower costs to expand access to prevention of early stages.
Continues after advertising
According to neurologist Richard Isaacson, who leads the research, the proposal is to democratize the care of brain health, allowing more people to monitor their risk and adopt measures even before the emergence of the first symptoms.